Postdoctoral Fellow
Caroline was born and raised in a small mountain town in Colorado. Her love for the mountains kept her in the state for her undergraduate studies. At Colorado College, she worked in the Biophysics lab of Phoebe Lostroh and Kristine Lang using atomic force microscopy to study bacterial morphology and DNA-dependent pili production of the soil-dwelling bacterium, Acinetobacter baylyi. This exposure to research sparked and fueled her interest in understanding the biological world around us at the microscopic and molecular levels. In her junior year, Caroline extended her research experience by traveling to Stockholm, Sweden to explore the roles of autophagy in cell survival and cell death at the University of Karolinska.
After completing her undergraduate studies, Caroline joined Kim Seed’s lab at the University of California, Berkeley for her PhD. She studied the parasitic mobile genetic element (or phage satellite), PLE, that hijacks and manipulates components of a phage to complete its own phage-like lifestyle. Her research of protein piracy and its role in constraining evolutionary escape from immunity led her to want to explore these concepts in mammalian viral systems.
In the Tenthorey lab, she hopes to explore how host cells can steal viral proteins and repurpose them for viral defense against HIV. Using high-throughput screening approaches and evolution experiments, Caroline hopes to understand how novel immune factors evolve from retroviral infections. She is interested in using these findings to help undercover the purpose of some of the fragmented retroviral sequences that litter mammalian genomes.
When not in lab, she enjoys hiking and spending time outdoors. As a big fan of neighborhood book/puzzle boxes, she’s probably reading a book by an author most people haven’t heard of or working on a random puzzle, hoping all of the pieces were still in the box.
After completing her undergraduate studies, Caroline joined Kim Seed’s lab at the University of California, Berkeley for her PhD. She studied the parasitic mobile genetic element (or phage satellite), PLE, that hijacks and manipulates components of a phage to complete its own phage-like lifestyle. Her research of protein piracy and its role in constraining evolutionary escape from immunity led her to want to explore these concepts in mammalian viral systems.
In the Tenthorey lab, she hopes to explore how host cells can steal viral proteins and repurpose them for viral defense against HIV. Using high-throughput screening approaches and evolution experiments, Caroline hopes to understand how novel immune factors evolve from retroviral infections. She is interested in using these findings to help undercover the purpose of some of the fragmented retroviral sequences that litter mammalian genomes.
When not in lab, she enjoys hiking and spending time outdoors. As a big fan of neighborhood book/puzzle boxes, she’s probably reading a book by an author most people haven’t heard of or working on a random puzzle, hoping all of the pieces were still in the box.
Contact: